My research interests have centered around immunology and molecular biology. In graduate school at Brandeis University, I cloned and studied the transporter protein, called FcRn, that carries IgG antibodies across the human placenta under Dr. Neil E. Simister.
Subsequent to my graduate work, new roles of FcRn have been discovered including extending the serum half-life of albumin as well as IgG antibody.
I also spend a good deal of my time doing pre-health advising, also known as "pre-med" advising. It's a wonderful part of my job to get to brag about our students to medical, dental, PA and other schools. It's never hard to find great things to say about our fine students.
In 2014, I offered the first "Pastors, Science and Faith" course, funded by a grant from The BIoLogos Foundation. It was so wonderful to be able to share the amazing world of modern science with pastors and discuss issues of science with them. This course will happen again in June, 2015. If we can find funding, I would love to be able to offer it in future years as well.
Spring15 Office Hours (KOSC 303) MWF 9:10-10:10, Thurs 1:30-4:30
P 978 867 4393
My postdoctoral work was under Dr. Hidde L. Ploegh at MIT and Harvard Medical School. Dr. Ploegh is currently at the Whitehead Institute back at MIT. I rejoined his research group for my Fall '06 Sabbatical. The lab continues to study aspects of immune function using a molecular and biochemical approach. During this sabbatical I worked closely with Dr. J. Christopher Love, helping to optimize a new system for analyzing the secretions of individual cells within a diverse population. Results of my work on the microengraving system with the Ploegh and Love labs were published in PNAS, Nature Protocols, and Journal of Immunological Methods.
In Fall 2011, I spent sabbatical time working in Chris Love's new lab in the Koch Institute for Integrative Cancer Research at MIT. I continue to develop the microengraving platform as a tool for use in immunological studies at Gordon College, in collaboration with the Love lab. I am also working on "new and improved" versions of antibody proteins. At the right is a print of antibody spots viewed with a slide scanner.
In Spring 2015, our department is proud to introduce some new equipment, including an Olympus laser scanning confocal microscope and two new IX-81 scopes, a Millipore Guava 5HT flow cytometer, and a Bio-Tek Cytation 3 Imaging Plate Reader. The cell culture room has doubled in size as well. These new facilities and equipment were funded by a grant from the Massachusetts Life Sciences Consortium (MLSC) to help prepare students for fields of medicine and biotechnology.